Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 102
Gene Symbol: ADAM10
ADAM10 		0.300 Biomarker disease CTD_human Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. 30820047 2019
Entrez Id: 9510
Gene Symbol: ADAMTS1
ADAMTS1 		0.300 Biomarker disease CTD_human Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. 30820047 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.300 Biomarker disease CTD_human Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. 30820047 2019
Entrez Id: 124152
Gene Symbol: IQCK
IQCK 		0.300 Biomarker disease CTD_human Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. 30820047 2019
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		0.300 Biomarker disease CTD_human Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. 30820047 2019
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.400 GeneticVariation disease BEFREE The genotype PSEN1 G206S appeared to correlate with the phenotype of EOAD with pure cognitive problems. 30814350 2019
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease BEFREE Mutations in presenilin 1 (PSEN1), presenilin 2 (PSEN2), and amyloid precursor protein (APP) are major genetic causes of early-onset Alzheimer's disease (EOAD). 30797548 2020
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		0.400 GeneticVariation disease BEFREE Our findings extend the mutation spectrum of EOAD and underline the clinical heterogeneity among PSEN1 and PSEN2 mutation carriers. 30797548 2020
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.400 GeneticVariation disease BEFREE Our findings extend the mutation spectrum of EOAD and underline the clinical heterogeneity among PSEN1 and PSEN2 mutation carriers. 30797548 2020
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 GeneticVariation disease BEFREE The identification of amyloid-β precursor protein (APP) pathogenic mutations in familial early onset Alzheimer's disease (AD), along with knowledge that amyloid-β (Aβ) was the principle protein component of senile plaques, led to the establishment of the amyloid cascade hypothesis. 30760863 2019
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 GeneticVariation disease BEFREE Mutations in the amyloid precursor protein (<i>APP</i>) gene were the first to be recognized as the cause of AD. 30510423 2018
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease BEFREE Taken together, these results identify an unrecognized physiological function of APP in promoting OB survival and bone formation, implicate APPswe acting as a dominant negative factor, and reveal a potential clinical value of NAC in treatment of AD-associated osteoporotic deficits. 30349052 2018
Entrez Id: 22861
Gene Symbol: NLRP1
NLRP1 		0.010 Biomarker disease BEFREE Taken together, these results identify an unrecognized physiological function of APP in promoting OB survival and bone formation, implicate APPswe acting as a dominant negative factor, and reveal a potential clinical value of NAC in treatment of AD-associated osteoporotic deficits. 30349052 2018
Entrez Id: 7504
Gene Symbol: XK
XK 		0.010 Biomarker disease BEFREE Taken together, these results identify an unrecognized physiological function of APP in promoting OB survival and bone formation, implicate APPswe acting as a dominant negative factor, and reveal a potential clinical value of NAC in treatment of AD-associated osteoporotic deficits. 30349052 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.300 Biomarker disease CTD_human Inhibition of miR-128 Abates Aβ-Mediated Cytotoxicity by Targeting PPAR-γ via NF-κB Inactivation in Primary Mouse Cortical Neurons and Neuro2a Cells. 30328325 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 3635
Gene Symbol: INPP5D
INPP5D 		0.300 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 10452
Gene Symbol: TOMM40
TOMM40 		0.300 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 23607
Gene Symbol: CD2AP
CD2AP 		0.300 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 100170222
Gene Symbol: SNAR-I
SNAR-I 		0.300 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 5819
Gene Symbol: NECTIN2
NECTIN2 		0.300 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 57091
Gene Symbol: CASS4
CASS4 		0.300 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development. 30319691 2018
Entrez Id: 5819
Gene Symbol: NECTIN2
NECTIN2 		0.300 Biomarker disease CTD_human Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development. 30319691 2018